[B] Aspidospermine or Quebrachine is derived from the
Chilian "white Quebracho" (Aspidospermia Quebracho). At
Santigo de Chile the bark is used as a substitute for
Cinchona as a febrifuge. The alkaloid forms salts with
Citric, Hydrochloric and Sulphuric acids.
PREPARATION.--Trituration of the alkaloid.
(Dr. Edwin M. Hale communicated the following concerning
this alkaloid to the Homoeopathic Recorder for 1889):
Dyspnoea.--This alkaloid is from the South American
tree--Quebracho. The maximum dose, according to Merck, is 1/10th
grain. I use the 1/500th trituration, which I find most efficient in
doses of 2 to 5 grains.
CASE I.--A boy of ten. The attacks of spasmodic dyspnoea were a sequel
of hay fever. The aggravation was at night, when lying down, or sleep
was impossible. I tried Ipecac and Arsenic, but with no effect.
Aralia, also. (I never had any curative or palliative effects from
Prescribed Aspidospermine, 1/500th trituration, 2 grains every two
hours, all day. The night was comfortable, could lie down and sleep.
Continued the remedy for four days, when he was so much better that the
medicine was suspended.
CASE II.--Cardiac dyspnoea in a man of 60. Valvular disease,
hypertrophy with dilatation. Distressing difficulty of breathing from
the slightest exertion; had to sit upright day and night. Face livid
from venous stasis. Strophanthus regulated and strengthened the
heart's action, but only slightly benefited the dyspnoea. Five grains
of Aspidospermine, 1/500th trituration, every two hours effected a
marvellous change. He could walk about the house and out to his carriage
with but little discomfort. He has now continued it three weeks.
Observes no unpleasant symptoms. Can lie on his back and right side and
is very grateful for the relief. It seems to act as well as an aid to
Digitalis, or Strophanthus, in cardiac dyspnoea.